This medicine is used long-term to prevent asthma. It is not used to relieve sudden asthma attacks.

Advair Uses
This medicine is used long-term to prevent asthma. It is not used to relieve sudden asthma attacks.

How to Take Advair
Fluticasone and salmeterol comes as a powder to inhale only by mouth using a special inhaler device. It usually is used twice a day, in the morning and evening approximately 12 hours apart. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use fluticasone and salmeterol exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor. Fluticasone and salmeterol controls asthma but does not cure it. It may take a week or longer before you feel the full benefit of fluticasone and salmeterol. Continue to use fluticasone and salmeterol even if you feel well. Do not stop using fluticasone and salmeterol without talking to your doctor. Before you use fluticasone and salmeterol inhalation for the first time, read the written instructions that come with it. Ask your doctor, pharmacist, or respiratory therapist to show you how to use the inhaler. Practice using your inhaler while he or she watches. To use the inhaler, follow these steps: * Hold the inhalation device in one hand, and put the thumb of your other hand on the thumbgrip. Push your thumb away from you as far as it will go until the mouthpiece appears and snaps into position. * Hold the inhalation device in a horizontal position with the mouthpiece toward you. Slide the lever away from you as far as it will go until it clicks. * Every time the lever is pushed back, a dose is ready to inhale. You will see the number in the dose counter go down. Do not waste doses by closing the device, playing with the lever, or advancing the lever more than once. * Hold the inhalation device level and away from your mouth, and breathe out as far as you comfortably can. * Put the mouthpiece to your lips. Breathe in quickly and deeply though the inhalation device, not through your nose. * Remove the inhalation device from your mouth, and hold your breath for 10 seconds or as long as you comfortably can. Breathe out slowly. * Put your thumb on the thumbgrip and slide it back toward you as far as it will go. The device will click shut. * Rinse your mouth with water.Never exhale into the inhalation device. Never take the device apart. Never wash the mouthpiece or any part of the device. Keep the device dry. Do not use the device with a spacer.

Advair Side Effects
Fluticasone and salmeterol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: * runny nose * sneezing * sore throat * hoarseness * sinus pain * cough * headache * upset stomach * vomiting * diarrhea * stomach pain * muscle and bone pain Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately: * hives * skin rash * itching * swelling of the face, throat, tongue, lips, hands, feet, ankles, or lower legs * choking or difficulty swallowing * increased difficulty breathing * less relief from your short-acting inhaler * need to use more puffs of your short-acting inhaler or need to use it more often * decrease in peak flow measurements * pounding or fast heartbeat * chest pain * nervousness * tremor * restlessness * loss of vision * white patches in the mouthFluticasone and salmeterol may cause children to grow more slowly. If you think that your child who is using fluticasone and salmeterol is not growing properly, talk to your child's doctor. Fluticasone and salmeterol may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

Precautions for taking Advair
Before using fluticasone and salmeterol, * tell your doctor and pharmacist if you are allergic to fluticasone (Flonase, Flovent), salmeterol (Serevent), or any other medications. * do not take formoterol (Foradil), salmeterol (Serevent), or regularly scheduled (for example, four-times-a-day) short-acting beta-agonists such as albuterol (Proventil, Ventolin) while taking fluticasone and salmeterol. * tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: antifungals such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); beta-blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); cimetidine (Tagamet); clarithromycin (Biaxin); cyclosporine (Neoral, Sandimmune); danazol (Danocrine); delavirdine (Rescriptor); diltiazem (Cardizem, Dilacor, Tiazac); diuretics (water pills); erythromycin (E.E.S., E-Mycin, Erythrocin); fluoxetine (Prozac, Sarafem); fluvoxamine (Luvox); HIV protease inhibitors such as indinavir (Crixivan) and ritonavir (Norvir); isoniazid (INH, Nydrazid); metronidazole (Flagyl); nefazodone (Serzone); oral contraceptives (birth control pills); troleandomycin (TAO); verapamil (Calan, Covera, Isoptin, Verelan); and zafirlukast (Accolate). Also tell your doctor and pharmacist if you are taking the following medications or have stopped taking them during the past 2 weeks: antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); and monoamine oxidase (MAO) inhibitors, including phenelzine (Nardil) and tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. * tell your doctor if you have or have ever had heart or liver disease, high blood pressure, convulsions, an overactive thyroid (hyperthyroidism), diabetes, or tuberculosis, and if you have a herpes eye infection or a fungal, viral, or bacterial infection (except an infection of the skin). * tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using fluticasone and salmeterol, call your doctor. * if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking fluticasone and salmeterol. * do not use fluticasone and salmeterol during a sudden asthma attack. You should have a fast-acting inhaler such as albuterol (Proventil, Ventolin) to use during asthma attacks. * avoid exposure to chickenpox or measles. If you are exposed to these diseases, call your doctor immediately. You may need to get a vaccine to protect you from these infections.

Advair Drug Interactions
Talk to your doctor about drinking grapefruit juice while taking this medicine.

Missed Dosage
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one

Storage of Advair
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away the inhalation device 1 month after you remove it from the foil overwrap or after every blister has been used (when the dose indicator reads 0), whichever comes first. Talk to your pharmacist about the proper disposal of your medication.

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